Protein Name:
Vinculin
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UniprotKB/SwissProt ID: P18206 (P18206)
Gene Name:
VCL
Organism: Homo sapiens (Human)
Function: Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane. Cell junction, adherens junction. Cell junction, focal adhesion. Cytoplasm, cytoskeleton. Cell membrane, sarcolemma. Cell projection, podosome
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P18206
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
1018 |
GSGTKRALIQ C AKDIAKASDE |
CCCCCCCCHH H HHHHHHHHCC |
3.94% |
|
| 2 |
1053 |
KRIRTNLLQV C ERIPTISTQL |
CCCCCCCCHH H HHHHHHHHCC |
1.55% |
25040305
2212679
|
| 3 |
325 |
GKERREILGT C KMLGQMTDQV |
CCCCCCCCHH H HHHHHHHHCC |
2.01% |
|
| 4 |
422 |
LAEARKIAEL C DDPKERDDIL |
CCCCCCCCHH H HHHHHHHHCC |
4.14% |
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| 5 |
545 |
GPYRQDLLAK C DRVDQLTAQL |
CCCCCCCCHH H HHHHHHHHCC |
3.16% |
25040305
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| 6 |
85 |
PPAFIKVENA C TKLVQAAQML |
CCCCCCCCHH H HHHHHHHHCC |
5.34% |
22178444
16648260
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