Protein Name:
Acetyl-CoA acetyltransferase, mitochondrial
|
UniprotKB/SwissProt ID: P17764 (P17764)
Gene Name:
Acat1
Organism: Rattus norvegicus (Rat)
Function: This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA. Thereby, it plays a major role in ketone body metabolism
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion
|
|
|
Graphical Visualization of S-nitrosylation Sites:
|
|
The S-nitrosylation sites of P17764
|
| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
116 |
LGAGLPIATP C TTVNKVCASG |
|
|
|
| 2 |
123 |
ATPCTTVNKV C ASGMKAIMMA |
|
|
|
|