Protein Name:
Triosephosphate isomerase
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UniprotKB/SwissProt ID: P17751 (P17751)
Gene Name:
Tpi1
Organism: Mus musculus (Mouse)
Function: Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P17751
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
127 |
ALAEGLGVIA C IGEKLDEREA |
CCCCHHHCCC C EEECCCCCCC |
24.64% |
21278135
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| 2 |
21 |
GNWKMNGRKK C LGELICTLNA |
CCCCHHHCCC C EEECCCCCCC |
52.59% |
|
| 3 |
218 |
IYGGSVTGAT C KELASQPDVD |
CCCCHHHCCC C EEECCCCCCC |
3.44% |
20925432
21278135
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| 4 |
67 |
DPKIAVAAQN C YKVTNGAFTG |
CCCCHHHCCC C EEECCCCCCC |
39.01% |
21278135
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