Protein Name:
Hydroxymethylglutaryl-CoA synthase, cytoplasmic
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UniprotKB/SwissProt ID: P17425 (P17425)
Gene Name:
Hmgcs1
Organism: Rattus norvegicus (Rat)
Function: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is converted by HMG-CoA reductase (HMGCR) into mevalonate, a precursor for cholesterol synthesis
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P17425
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
224 |
PVVDGKLSIQ C YLSALDRCYS |
CCCCCCCCCC H HCCCCCEEEE |
3.35% |
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| 2 |
232 |
IQCYLSALDR C YSVYRKKIRA |
CCCCCCCCCC H HCCCCCEEEE |
2.72% |
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| 3 |
417 |
DLKSRLDSRT C VAPDVFAENM |
CCCCCCCCCC H HCCCCCEEEE |
2.09% |
22178444
19101475
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