Protein Name:
Tryptophan--tRNA ligase, cytoplasmic
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UniprotKB/SwissProt ID: P17248 (P17248)
Gene Name:
WARS1
Organism: Bos taurus (Bovine)
Function: T1-TrpRS has aminoacylation activity while T2-TrpRS lacks it. T1-TrpRS and T2-TrpRS possess angiostatic activity. T2-TrpRS inhibits fluid shear stress-activated responses of endothelial cells. Regulates ERK, Akt, and eNOS activation pathways that are associated with angiogenesis, cytoskeletal reorganization and shear stress-responsive gene expression (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P17248
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
279 |
KGIFGFTDSD C IGKISFPAIQ |
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| 2 |
310 |
QIFRDRTDVQ C LIPCAIDQDP |
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| 3 |
314 |
DRTDVQCLIP C AIDQDPYFRM |
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