Protein Name:
Bactericidal permeability-increasing protein
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UniprotKB/SwissProt ID: P17213 (P17213)
Gene Name:
BPI
Organism: Homo sapiens (Human)
Function: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Secreted. Cytoplasmic granule membrane
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Graphical Visualization of S-nitrosylation Sites:
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