Protein Name:
Methylated-DNA--protein-cysteine methyltransferase
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UniprotKB/SwissProt ID: P16455 (P16455)
Gene Name:
MGMT
Organism: Homo sapiens (Human)
Function: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P16455
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
145 |
RGNPVPILIP C HRVVCSSGAV |
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| 2 |
150 |
PILIPCHRVV C SSGAVGNYSG |
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