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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Epithelial cell adhesion molecule

UniprotKB/SwissProt ID: P16422 (P16422)

Gene Name: EPCAM

Organism: Homo sapiens (Human)

Function: May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Lateral cell membrane. Cell junction, tight junction

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR049420 EPCAM-Trop-2_C
IPR043406 EPCAM/Trop-2
IPR041630 EpCAM_N
IPR000716 Thyroglobulin_1
IPR036857 Thyroglobulin_1_sf