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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Spectrin alpha chain, non-erythrocytic 1

UniprotKB/SwissProt ID: P16086 (P16086)

Gene Name: Sptan1

Organism: Rattus norvegicus (Rat)

Function: Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton. Cytoplasm, cell cortex

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR035825 Alpha_Spectrin_SH3
IPR011992 EF-hand-dom_pair
IPR014837 EF-hand_Ca_insen
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
IPR018159 Spectrin/alpha-actinin
IPR002017 Spectrin_repeat

The S-nitrosylation sites of P16086

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 1314 PESAEDLKEK C TELNQAWTSL   
2 1454 CLELQLFHRD C EQAENWMAAR   
3 158 AQKLVQYLRE C EDVMDWINDK   
4 1622 MGNSLIERGA C AGSEDAVKAR   
5 1930 TVHKDRVNDV C TNGQDLIKKN   
6 2120 AEEDLTDPVR C NSLEEIKALR   
7 2233 ETRTYLLDGS C MVEESGTLES   
8 2441 QNLTREQADY C VSHMKPYVDG   
9 315 AALEDKVKAL C AEADRLQQSH