Protein Name:
Guanine nucleotide-binding protein alpha-2 subunit
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UniprotKB/SwissProt ID: P16051 (P16051)
Gene Name:
gpaB
Organism: Dictyostelium discoideum (Social amoeba)
Function: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G alpha-2 is required for the early aggregation process and most of the known cAMP receptor-mediated responses (PubMed:2539262). Interacts with downstream effector gflB, a Rap guanine nucleotide exchange factor, to regulate the balance between Ras and Rap signaling at the leading edge of chemotaxing cells (PubMed:27237792)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization:
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Graphical Visualization of S-nitrosylation Sites:
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