dbSNO 2.0

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Protein Name: Metalloproteinase inhibitor 2

UniprotKB/SwissProt ID: P16035 (P16035)

Gene Name: TIMP2

Organism: Homo sapiens (Human)

Function: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Secreted

Graphical Visualization of S-nitrosylation Sites:

InterPro ID	Domain Name
IPR001134	Netrin_domain
IPR001820	TIMP
IPR008993	TIMP-like_OB-fold
IPR027465	TIMP_C
IPR030490	TIMP_CS

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