UniprotKB/SwissProt ID: P15409 (P15409)
Gene Name:
Rho
Organism: Mus musculus (Mouse)
Function: Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth (PubMed:9020854). Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (PubMed:27353443)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Membrane. Cell projection, cilium, photoreceptor outer segment
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