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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Ezrin

UniprotKB/SwissProt ID: P15311 (P15311)

Gene Name: EZR

Organism: Homo sapiens (Human)

Function: Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Apical cell membrane. Cell projection. Cell projection, microvillus membrane. Cell projection, ruffle membrane. Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Cell projection, microvillus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR019749 Band_41_domain
IPR011174 ERM
IPR011259 ERM_C_dom
IPR041789 ERM_FERM_C
IPR046810 ERM_helical
IPR000798 Ez/rad/moesin-like
IPR014352 FERM/acyl-CoA-bd_prot_sf
IPR035963 FERM_2
IPR019748 FERM_central
IPR019747 FERM_CS
IPR000299 FERM_domain
IPR018979 FERM_N
IPR018980 FERM_PH-like_C
IPR008954 Moesin_tail_sf
IPR011993 PH-like_dom_sf
IPR029071 Ubiquitin-like_domsf

The S-nitrosylation sites of P15311

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 117 KEGILSDEIY C PPETAVLLGS