Protein Name:
Microtubule-associated protein 1B
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UniprotKB/SwissProt ID: P15205 (P15205)
Gene Name:
Map1b
Organism: Rattus norvegicus (Rat)
Function: Required for proper microtubule dynamics. Plays a role in the cytoskeletal changes that accompany neuronal differentiation and neurite extension (By similarity). Possibly MAP1B binds to at least two tubulin subunits in the polymer, and this bridging of subunits might be involved in nucleating microtubule polymerization and in stabilizing microtubules. Acts as a positive cofactor in DAPK1-mediated autophagic vesicle formation and membrane blebbing (By similarity). Facilitates tyrosination of alpha-tubulin in neuronal microtubules. Required for synaptic maturation (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytoskeleton. Cytoplasm. Synapse. Cell projection, dendritic spine. Cytoplasm
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P15205
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
1303 |
GVTQAVVEEH C ASPEEKTLEV |
CCEEEEEECC C CCCCCCCCCC |
29.99% |
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| 2 |
190 |
PANKASLTLF C PEEGDWKNSN |
CCEEEEEECC C CCCCCCCCCC |
4.69% |
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| 3 |
1910 |
EKTERTIKSP C DSGYSYETIE |
CCEEEEEECC C CCCCCCCCCC |
46.47% |
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| 4 |
1997 |
TEDGGHTLGD C SYSYETTEKI |
CCEEEEEECC C CCCCCCCCCC |
22.92% |
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| 5 |
2034 |
TTRSPDTSAY C YETMEKITKT |
CCEEEEEECC C CCCCCCCCCC |
37.81% |
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| 6 |
2457 |
VVMQDESFPA C KIEL------ |
CCEEEEEECC C CCCCCCCCCC |
7.02% |
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| 7 |
382 |
IKMKRSTEEA C FTLQYLNKLS |
CCEEEEEECC C CCCCCCCCCC |
11.15% |
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