Protein Name:
Ras-related C3 botulinum toxin substrate 2
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UniprotKB/SwissProt ID: P15153 (P15153)
Gene Name:
RAC2
Organism: Homo sapiens (Human)
Function: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state (PubMed:30723080). In its active state, binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Regulatory subunit of the phagocyte NADPH oxidase complex that mediates the transfer of electrons from cytosolic NADPH to O2 to produce the superoxide anion (O2(-)) (PubMed:1660188)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P15153
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
105 |
AKWFPEVRHH C PSTPIILVGT |
CCCCEEEEEC C CCCCCEEEEE |
2.02% |
22126794
2212679
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| 2 |
157 |
KEIDSVKYLE C SALTQRGLKT |
CCCCEEEEEC C CCCCCEEEEE |
2.38% |
37478858
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| 3 |
178 |
VFDEAIRAVL C PQPTRQQKRA |
CCCCEEEEEC C CCCCCEEEEE |
2.06% |
24105792
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| 4 |
6 |
-----MQAIK C VVVGDGAVGK |
CCCCEEEEEC C CCCCCEEEEE |
1.99% |
2212679
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