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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Glucosidase 2 subunit beta

UniprotKB/SwissProt ID: P14314 (P14314)

Gene Name: PRKCSH

Organism: Homo sapiens (Human)

Function: Regulatory subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins (PubMed:10929008). Required for efficient PKD1/Polycystin-1 biogenesis and trafficking to the plasma membrane of the primary cilia (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Endoplasmic reticulum

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR039794 Gtb1-like
IPR036055 LDL_receptor-like_sf
IPR009011 Man6P_isomerase_rcpt-bd_dom_sf
IPR044865 MRH_dom
IPR036607 PRKCSH
IPR028146 PRKCSH_N

The S-nitrosylation sites of P14314

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 471 SAMKYEQGTG C WQGPNRSTTV   
2 512 YLMELMTPAA C PEPPPEAPTE