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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Sodium/potassium-transporting ATPase subunit beta-1

UniprotKB/SwissProt ID: P14094 (P14094)

Gene Name: Atp1b1

Organism: Mus musculus (Mouse)

Function: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane Involved in cell adhesion and establishing epithelial cell polarity

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell membrane. Apical cell membrane. Cell membrane, sarcolemma

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR000402 Na/K_ATPase_sub_beta
IPR038702 Na/K_ATPase_sub_beta_sf

The S-nitrosylation sites of P14094

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 175 DSYGYREGKP C IIIKLNRVLG  CCCCCCCCCC C CCCEEEECHH  3.88%
2 214 KYNPNVLPVQ C TGKRDEDKDK  CCCCCCCCCC C CCCEEEECHH  5.73% 24895380
22588120
3 277 LTVDTEIRVE C KAYGENIGYS  CCCCCCCCCC C CCCEEEECHH  2.53%