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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Acylamino-acid-releasing enzyme

UniprotKB/SwissProt ID: P13798 (P13798)

Gene Name: APEH

Organism: Homo sapiens (Human)

Function: This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus (PubMed:10719179, PubMed:1740429, PubMed:2006156). It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser (By similarity). Also, involved in the degradation of oxidized and glycated proteins (PubMed:10719179)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR011042 6-blade_b-propeller_TolB-like
IPR045550 AARE_N
IPR029058 AB_hydrolase_fold
IPR002471 Pept_S9_AS
IPR001375 Peptidase_S9_cat

The S-nitrosylation sites of P13798

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 292 LYYVDLIGGK C ELLSDDSLAV   
2 30 LSRQPALSAA C LGPEVTTQYG   
3 368 GIYCSLLPLG C WSADSQRVVF