\
logo
  Home | Contact us | Browse | Quick Search by UniProtKB ID, Keyword, PDBID

Menu:

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Read more...


Protein Name: Uridine 5'-monophosphate synthase

UniprotKB/SwissProt ID: P13439 (P13439)

Gene Name: Umps

Organism: Mus musculus (Mouse)

Function: Bifunctional enzyme catalyzing the last two steps of de novo pyrimidine biosynthesis, orotate phosphoribosyltransferase (OPRT), which converts orotate to orotidine-5'-monophosphate (OMP), and orotidine-5'-monophosphate decarboxylase (ODC), the terminal enzymatic reaction that decarboxylates OMP to uridine monophosphate (UMP)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR013785 Aldolase_TIM
IPR014732 OMPdecase
IPR018089 OMPdecase_AS
IPR001754 OMPdeCOase_dom
IPR023031 OPRT
IPR004467 Or_phspho_trans_dom
IPR000836 PRibTrfase_dom
IPR029057 PRTase-like
IPR011060 RibuloseP-bd_barrel

The S-nitrosylation sites of P13439

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 174 QAQGIRLHAV C TLSQMLEILQ  CHHHHHHHHH H HHHCCCCEEC  3.08% 20925432