Protein Name:
Nuclear receptor subfamily 2 group C member 1
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UniprotKB/SwissProt ID: P13056 (P13056)
Gene Name:
NR2C1
Organism: Homo sapiens (Human)
Function: Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Together with NR2C2, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription. Also activator of OCT4 gene expression. May be involved in stem cell proliferation and differentiation. Mediator of retinoic acid-regulated preadipocyte proliferation
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Nucleus, PML body
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P13056
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
265 |
VLMTSDKAES C QGDLSTLANV |
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