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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: cAMP-dependent protein kinase type II-beta regulatory subunit

UniprotKB/SwissProt ID: P12369 (P12369)

Gene Name: Prkar2b

Organism: Rattus norvegicus (Rat)

Function: Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Cell membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR050503 cAMP-dep_PK_reg_su-like
IPR012198 cAMP_dep_PK_reg_su
IPR003117 cAMP_dep_PK_reg_su_I/II_a/b
IPR018488 cNMP-bd_CS
IPR000595 cNMP-bd_dom
IPR018490 cNMP-bd_dom_sf
IPR014710 RmlC-like_jellyroll

The S-nitrosylation sites of P12369

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 114 INRFTRRASV C AEAYNPDEEE   
2 209 IYVKCDGVGR C VGNYDNRGSF   
3 386 VQAFERLLGP C MEIMKRNIAT