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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Serotransferrin

UniprotKB/SwissProt ID: P12346 (P12346)

Gene Name: Tf

Organism: Rattus norvegicus (Rat)

Function: Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Secreted

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR030685 Serotransferrin_mammal
IPR016357 Transferrin
IPR001156 Transferrin-like_dom
IPR018195 Transferrin_Fe_BS

The S-nitrosylation sites of P12346

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 137 QLNQLQGKKS C HTGLGRSAGW   
2 246 KADRDQYELL C LDNTRKPVDQ   
3 28 LAVPDKTVKW C AVSEHENTKC   
4 542 GYNGYTGAFQ C LVEKGDVAFV   
5 67 ACVKKTSYQD C IKAISGGEAD   
6 693 KCSTSRLLEA C TFHKS-----