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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Ornithine decarboxylase

UniprotKB/SwissProt ID: P11926 (P11926)

Gene Name: ODC1

Organism: Homo sapiens (Human)

Function: Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR009006 Ala_racemase/Decarboxylase_C
IPR022643 De-COase2_C
IPR022657 De-COase2_CS
IPR022644 De-COase2_N
IPR022653 De-COase2_pyr-phos_BS
IPR000183 Orn/DAP/Arg_de-COase
IPR002433 Orn_de-COase
IPR029066 PLP-binding_barrel

The S-nitrosylation sites of P11926

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 114 PPERIIYANP C KQVSQIKYAA  CCCCCCCCCC C CCCCCCCCHH  4.89%
2 360 YYSSSIWGPT C DGLDRIVERC  CCCCCCCCCC C CCCCCCCCHH  4.38% 11461922