Protein Name:
Pyruvate carboxylase, mitochondrial
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UniprotKB/SwissProt ID: P11498 (P11498)
Gene Name:
PC
Organism: Homo sapiens (Human)
Function: Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion matrix
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P11498
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
131 |
LSERADFAQA C QDAGVRFIGP |
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| 2 |
56 |
GEIAIRVFRA C TELGIRTVAI |
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| 3 |
622 |
FDVAMRFLYE C PWRRLQELRE |
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| 4 |
663 |
NYPDNVVFKF C EVAKENGMDV |
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| 5 |
739 |
ELVRAGTHIL C IKDMAGLLKP |
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