Protein Name:
Uridine 5'-monophosphate synthase
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UniprotKB/SwissProt ID: P11172 (P11172)
Gene Name:
UMPS
Organism: Homo sapiens (Human)
Function: Bifunctional enzyme catalyzing the last two steps of de novo pyrimidine biosynthesis, orotate phosphoribosyltransferase (OPRT), which converts orotate to orotidine-5'-monophosphate (OMP), and orotidine-5'-monophosphate decarboxylase (ODC), the terminal enzymatic reaction that decarboxylates OMP to uridine monophosphate (UMP)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization:
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P11172
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
174 |
QAHGIRLHSV C TLSKMLEILE |
CHHHHHHHHH H HCCCCCCCCC |
3.38% |
19483679
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| 2 |
255 |
RLMQKKETNL C LSADVSLARE |
CHHHHHHHHH H HCCCCCCCCC |
2.83% |
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| 3 |
278 |
QLADALGPSI C MLKTHVDILN |
CHHHHHHHHH H HCCCCCCCCC |
2.83% |
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| 4 |
304 |
VMKELITLAK C HEFLIFEDRK |
CHHHHHHHHH H HCCCCCCCCC |
2.86% |
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