Protein Name:
Protein 4.1
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UniprotKB/SwissProt ID: P11171 (P11171)
Gene Name:
EPB41
Organism: Homo sapiens (Human)
Function: Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction. Recruits DLG1 to membranes. Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase (PubMed:23870127)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Nucleus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P11171
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
179 |
EIKEGEGLEE C SKIEVKEESP |
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| 2 |
39 |
GQQEPQQEES C QTAAEGDNWC |
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