UniprotKB/SwissProt ID: P10730 (P10730)
Gene Name:
NPR3
Organism: Bos taurus (Bovine)
Function: Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. Acts as a regulator of osteoblast differentiation and bone growth by binding to its ligand osteocrin, thereby preventing binding between NPR3/NPR-C and natriuretic peptides, leading to increase cGMP production
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane
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