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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Glutathione S-transferase Mu 1

UniprotKB/SwissProt ID: P10649 (P10649)

Gene Name: Gstm1

Organism: Mus musculus (Mouse)

Function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). Participates in the formation of novel hepoxilin regioisomers

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR010987 Glutathione-S-Trfase_C-like
IPR036282 Glutathione-S-Trfase_C_sf
IPR040079 Glutathione_S-Trfase
IPR004045 Glutathione_S-Trfase_N
IPR004046 GST_C
IPR003081 GST_mu
IPR050213 GST_superfamily
IPR036249 Thioredoxin-like_sf

The S-nitrosylation sites of P10649

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 115 MDTRMQLIML C YNPDFEKQKP  CCCEEEEEEC C CCCHHHHHHH  1.38% 21278135
2 174 LDQYRMFEPK C LDAFPNLRDF  CCCEEEEEEC C CCCHHHHHHH  6.43% 21278135