Protein Name:
Cathepsin B
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UniprotKB/SwissProt ID: P10605 (P10605)
Gene Name:
Ctsb
Organism: Mus musculus (Mouse)
Function: Thiol protease which is believed to participate in intracellular degradation and turnover of proteins (By similarity). Cleaves matrix extracellular phosphoglycoprotein MEPE (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen (PubMed:12782676). Has also been implicated in tumor invasion and metastasis (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Lysosome. Melanosome. Secreted, extracellular space. Apical cell membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P10605
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
105 |
TIGQIRDQGS C GSCWAFGAVE |
CHHHHHHHHH H HHHHCCCCCC |
6.26% |
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| 2 |
211 |
EGDTPRCNKS C EAGYSPSYKE |
CHHHHHHHHH H HHHHCCCCCC |
4.42% |
21278135
|
| 3 |
319 |
FFKILRGENH C GIESEIVAGI |
CHHHHHHHHH H HHHHCCCCCC |
9.9% |
22178444
21278135
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| 4 |
59 |
NVDISYLKKL C GTVLGGPKLP |
CHHHHHHHHH H HHHHCCCCCC |
6.2% |
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| 5 |
93 |
TFDAREQWSN C PTIGQIRDQG |
CHHHHHHHHH H HHHHCCCCCC |
2.34% |
24926564
22588120
21278135
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