Protein Name:
RNA-binding protein RO60
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UniprotKB/SwissProt ID: P10155 (P10155)
Gene Name:
RO60
Organism: Homo sapiens (Human)
Function: RNA-binding protein that binds to misfolded non-coding RNAs, pre-5S rRNA, and several small cytoplasmic RNA molecules known as Y RNAs (PubMed:18056422, PubMed:26382853). Binds to endogenous Alu retroelements which are induced by type I interferon and stimulate porinflammatory cytokine secretion (PubMed:26382853). Regulates the expression of Alu retroelements as well as inflammatory genes (PubMed:26382853). May play roles in cilia formation and/or maintenance (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P10155
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
305 |
EPGNSEVSLV C EKLCNEKLLK |
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| 2 |
38 |
TDMNRLHRFL C FGSEGGTYYI |
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37478858
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| 3 |
499 |
KMDIPAKLIV C GMTSNGFTIA |
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| 4 |
520 |
DPDDRGMLDM C GFDTGALDVI |
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| 5 |
71 |
LIRLIEDGRG C EVIQEIKSFS |
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