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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: D-tagatose-1,6-bisphosphate aldolase subunit GatY

UniprotKB/SwissProt ID: P0C8J6 (P0C8J6)

Gene Name: gatY

Organism: Escherichia coli (strain K12)

Function: Catalytic subunit of the tagatose-1,6-bisphosphate aldolase GatYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP) (PubMed:11976750, PubMed:8955298). Requires GatZ subunit for full activity and stability (PubMed:11976750). Is involved in the catabolism of galactitol (PubMed:11976750, PubMed:8955298). Has a high aldolase activity for TBP and a very low one for fructose 1,6-bisphosphate (FBP) (PubMed:11976750)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR013785 Aldolase_TIM
IPR050246 Class_II_FBP_aldolase
IPR000771 FBA_II
IPR011288 TagBP_ald_KbaY/GatY
IPR023955 TagBP_aldolase_GatY

The S-nitrosylation sites of P0C8J6

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 124 ISRVKEVVDF C HRFDVSVEAE  CEEECHHHHH H HHHCCCEECC  1.63% 22178444
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