Protein Name:
Ferritin heavy chain
|
UniprotKB/SwissProt ID: P09528 (P09528)
Gene Name:
Fth1
Organism: Mus musculus (Mouse)
Function: Stores iron in a soluble, non-toxic, readily available form (By similarity). Important for iron homeostasis (By similarity). Has ferroxidase activity (By similarity). Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation (By similarity). Also plays a role in delivery of iron to cells (PubMed:19154717). Mediates iron uptake in capsule cells of the developing kidney (PubMed:19154717). Degraded to release iron upon autophagy activation by nutrient starvation (PubMed:25327288)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Cytoplasmic vesicle, autophagosome. Autolysosome
|
|
|
Graphical Visualization of S-nitrosylation Sites:
|
|
The S-nitrosylation sites of P09528
|
| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
103 |
DWESGLNAME C ALHLEKSVNQ |
CCCCCHHHHH H HHHHHHHHHH |
2.91% |
|
| 2 |
131 |
LATDKNDPHL C DFIETYYLSE |
CCCCCHHHHH H HHHHHHHHHH |
3.5% |
20925432
|
|
