Protein Name:
Galectin-1
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UniprotKB/SwissProt ID: P09382 (P09382)
Gene Name:
LGALS1
Organism: Homo sapiens (Human)
Function: Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. Plays a negative role in Th17 cell differentiation via activation of the receptor CD69 (PubMed:24752896)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Secreted, extracellular space, extracellular matrix. Cytoplasm. Secreted
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P09382
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
131 |
MAADGDFKIK C VAFD------ |
CCCCCEEECC C CCCCCEEEEE |
2.8% |
22126794
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| 2 |
3 |
--------MA C GLVASNLNLK |
CCCCCEEECC C CCCCCEEEEE |
4.12% |
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| 3 |
43 |
LNLGKDSNNL C LHFNPRFNAH |
CCCCCEEECC C CCCCCEEEEE |
2.78% |
22178444
2212679
20140087
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| 4 |
61 |
NAHGDANTIV C NSKDGGAWGT |
CCCCCEEECC C CCCCCEEEEE |
4.15% |
18335467
2212679
20140087
22178444
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| 5 |
89 |
PFQPGSVAEV C ITFDQANLTV |
CCCCCEEECC C CCCCCEEEEE |
1.5% |
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