Protein Name:
U1 small nuclear ribonucleoprotein C
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UniprotKB/SwissProt ID: P09234 (P09234)
Gene Name:
SNRPC
Organism: Homo sapiens (Human)
Function: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P09234
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
25 |
HDSPSVRKTH C SGRKHKENVK |
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| 2 |
6 |
-----MPKFY C DYCDTYLTHD |
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| 3 |
9 |
--MPKFYCDY C DTYLTHDSPS |
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