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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: ATP-dependent 6-phosphofructokinase, muscle type

UniprotKB/SwissProt ID: P08237 (P08237)

Gene Name: PFKM

Organism: Homo sapiens (Human)

Function: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR009161 6-Pfructokinase_euk
IPR022953 ATP_PFK
IPR041914 PFK_vert-type
IPR015912 Phosphofructokinase_CS
IPR000023 Phosphofructokinase_dom
IPR035966 PKF_sf

The S-nitrosylation sites of P08237

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 114 NLVKRGITNL C VIGGDGSLTG   
2 170 GLVGSIDNDF C GTDMTIGTDS   
3 334 LLEGTPDTPA C VVSLSGNQAV   
4 351 NQAVRLPLME C VQVTKDVTKA   
5 631 KRGLVLRNEK C NENYTTDFIF   
6 709 RIFANTPDSG C VLGMRKRALV