\
logo
  Home | Contact us | Browse | Quick Search by UniProtKB ID, Keyword, PDBID

Menu:

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Read more...


Protein Name: Rho-related GTP-binding protein RhoC

UniprotKB/SwissProt ID: P08134 (P08134)

Gene Name: RHOC

Organism: Homo sapiens (Human)

Function: Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Regulates apical junction formation in bronchial epithelial cells

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell membrane. Cleavage furrow

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd
IPR001806 Small_GTPase
IPR003578 Small_GTPase_Rho

The S-nitrosylation sites of P08134

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 107 EKWTPEVKHF C PNVPIILVGN   
2 159 NRISAFGYLE C SAKTKEGVRE   
3 16 KKLVIVGDGA C GKTCLLIVFS   
4 20 IVGDGACGKT C LLIVFSKDQF