UniprotKB/SwissProt ID: P08111 (P08111)
Gene Name:
l(2)gl
Organism: Drosophila melanogaster (Fruit fly)
Function: Essential for the development of polarized epithelia, for cell polarity associated with asymmetric cell division of neuroblasts during development, and for oocyte polarity formation. Promotes the formation of actin-rich projections at the oocyte cortex and the posterior enrichment of par-1 which is required for oocyte polarization. Regulates the localization of axis-specifying morphogens such as stau and grk Has an essential role in control of cell proliferation and differentiation during development and could act as a tumor suppressor Has an accessory function in control of cell proliferation and differentiation during development
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cell cortex. Cytoplasm
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