Protein Name:
Profilin-1
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UniprotKB/SwissProt ID: P07737 (P07737)
Gene Name:
PFN1
Organism: Homo sapiens (Human)
Function: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytoskeleton
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P07737
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
128 |
GVHGGLINKK C YEMASHLRRS |
CCCHHHHHHH H CCCCCCCCEE |
3.57% |
25040305
2212679
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