Protein Name:
Calpain-1 catalytic subunit
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UniprotKB/SwissProt ID: P07384 (P07384)
Gene Name:
CAPN1
Organism: Homo sapiens (Human)
Function: Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction (PubMed:19617626, PubMed:21531719, PubMed:2400579). Proteolytically cleaves CTBP1 at 'Asn-375', 'Gly-387' and 'His-409' (PubMed:23707407). Cleaves and activates caspase-7 (CASP7) (PubMed:19617626)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Cell membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P07384
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
351 |
FMREFTRLEI C NLTPDALKSR |
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| 2 |
49 |
GQDYEQLRVR C LQSGTLFRDE |
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| 3 |
590 |
LRTKGFSLES C RSMVNLMDRD |
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| 4 |
678 |
LAVDFDNFVC C LVRLETMFRF |
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