Protein Name:
Cathepsin D
|
UniprotKB/SwissProt ID: P07339 (P07339)
Gene Name:
CTSD
Organism: Homo sapiens (Human)
Function: Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation (PubMed:27333034). Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Lysosome. Melanosome. Secreted, extracellular space
|
|
|
Graphical Visualization of S-nitrosylation Sites:
|
|
The S-nitrosylation sites of P07339
|
| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
290 |
ASGLTLCKEG C EAIVDTGTSL |
|
|
|
| 2 |
329 |
PLIQGEYMIP C EKVSTLPAIT |
|
|
|
|
