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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Creatine kinase M-type

UniprotKB/SwissProt ID: P07310 (P07310)

Gene Name: Ckm

Organism: Mus musculus (Mouse)

Function: Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR000749 ATP-guanido_PTrfase
IPR022415 ATP-guanido_PTrfase_AS
IPR022414 ATP-guanido_PTrfase_cat
IPR022413 ATP-guanido_PTrfase_N
IPR036802 ATP-guanido_PTrfase_N_sf
IPR014746 Gln_synth/guanido_kin_cat_dom

The S-nitrosylation sites of P07310

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 146 SIKGYTLPPH C SRGERRAVEK  CCCCCCCCCC C CCCCCHHHCC  3.51% 21278135
2 254 GNMKEVFRRF C VGLQKIEEIF  CCCCCCCCCC C CCCCCHHHCC  1.94% 21278135
3 283 WNEHLGYVLT C PSNLGTGLRG  CCCCCCCCCC C CCCCCHHHCC  2.8% 21278135
4 74 PGHPFIMTVG C VAGDEESYTV  CCCCCCCCCC C CCCCCHHHCC  1.32%