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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Major centromere autoantigen B

UniprotKB/SwissProt ID: P07199 (P07199)

Gene Name: CENPB

Organism: Homo sapiens (Human)

Function: Interacts with centromeric heterochromatin in chromosomes and binds to a specific 17 bp subset of alphoid satellite DNA, called the CENP-B box (PubMed:11726497). May organize arrays of centromere satellite DNA into a higher-order structure which then directs centromere formation and kinetochore assembly in mammalian chromosomes (Probable)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus. Chromosome, centromere

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR015115 CenpB_C
IPR050863 CenT-Element_Derived
IPR004875 DDE_SF_endonuclease_dom
IPR034882 Dimerisation_CENP-B_sf
IPR009057 Homeodomain-like_sf
IPR006600 HTH_CenpB_DNA-bd_dom
IPR007889 HTH_Psq

The S-nitrosylation sites of P07199

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 230 QATQRLSVLL C ANADGSEKLP   
2 259 KPRAGQAGLP C DYTANSKGGV   
3 65 SERKYGVAST C RKTNKLSPYD