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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: NADP-dependent malic enzyme
UniprotKB/SwissProt ID: P06801 (P06801)

Gene Name: Me1

Organism: Mus musculus (Mouse)

Function: Catalyzes the oxidative decarboxylation of (S)-malate in the presence of NADP(+) and divalent metal ions, and decarboxylation of oxaloacetate

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR046346 Aminoacid_DH-like_N_sf
IPR015884 Malic_enzyme_CS
IPR012301 Malic_N_dom
IPR037062 Malic_N_dom_sf
IPR012302 Malic_NAD-bd
IPR001891 Malic_OxRdtase
IPR036291 NAD(P)-bd_dom_sf
The S-nitrosylation sites of P06801
No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 110 IVYTPTVGLA C QQYSLAFRKP  CCCCCCCCCC C HHCCEECCCC  2.89% 21278135
2 164 ERILGLGDLG C NGMGIPVGKL  CCCCCCCCCC C HHCCEECCCC  5.31% 21278135
3 415 ALSNPTSKAE C SAEQCYKVTK  CCCCCCCCCC C HHCCEECCCC  5.81%
4 420 TSKAECSAEQ C YKVTKGRAIF  CCCCCCCCCC C HHCCEECCCC  2.4%
5 468 FPGVALGVVA C GLRHIDDKVF  CCCCCCCCCC C HHCCEECCCC  3.4% 21278135
6 47 QLNIHGLLPP C IISQELQVLR  CCCCCCCCCC C HHCCEECCCC  3.99% 21278135