Protein Name:
ATP-dependent translocase ABCB1
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UniprotKB/SwissProt ID: P06795 (P06795)
Gene Name:
Abcb1b
Organism: Mus musculus (Mouse)
Function: Translocates drugs and phospholipids across the membrane. Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides and sphingomyelins. Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane. Apical cell membrane. Cytoplasm
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Graphical Visualization of S-nitrosylation Sites:
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