Protein Name:
Low affinity immunoglobulin epsilon Fc receptor
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UniprotKB/SwissProt ID: P06734 (P06734)
Gene Name:
FCER2
Organism: Homo sapiens (Human)
Function: Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B cells. On B cells, initiates IgE-dependent antigen uptake and presentation to T cells (PubMed:2167225). On macrophages, upon IgE binding and antigen cross-linking induces intracellular killing of parasites through activation of L-Arginine-nitric oxide pathway (PubMed:7544003)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane. Cell membrane. Secreted
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Graphical Visualization of S-nitrosylation Sites:
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