UniprotKB/SwissProt ID: P06525 (P06525)
Gene Name:
ADH1
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Alcohol dehydrogenase catalyzing the reduction of toxic aldehydes to the corresponding alcohols (PubMed:38308388). Mostly active on ethanol (EtOH), but exhibits broad substrate selectivity for primary and secondary alcohols (e.g. cinnamyl alcohol, octanol, geraniol, butanol, propyl alcohol, pentanol, isopentanol, ethylene glycol, isopropanol, methanol and tertiary butyl alcohol) (PubMed:23707506, PubMed:38308388). Also catalyzes the reverse reaction to convert allyl alcohol to highly toxic acryl-aldehyde (PubMed:20508152). Required for survival and acclimation in hypoxic conditions, especially in roots (PubMed:12857811, PubMed:9880346). Not able to catalyze NADH-dependent degradation of S-nitrosoglutathione (GSNO) (PubMed:38308388)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm
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