UniprotKB/SwissProt ID: P05155 (P05155)
Gene Name:
SERPING1
Organism: Homo sapiens (Human)
Function: Serine protease inhibitor, which acrs as a regulator of the classical complement pathway (PubMed:10946292, PubMed:11527969, PubMed:3458172, PubMed:6416294). Forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases (PubMed:10946292, PubMed:3458172, PubMed:6416294). May also regulate blood coagulation, fibrinolysis and the generation of kinins (PubMed:8495195). Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein (PubMed:8495195)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Secreted
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