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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Aromatic-L-amino-acid decarboxylase

UniprotKB/SwissProt ID: P05031 (P05031)

Gene Name: Ddc

Organism: Drosophila melanogaster (Fruit fly)

Function: Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (L-DOPA) to dopamine and L-5-hydroxytryptophan (5-HTP) to serotonin (PubMed:20098687). Catalyzes the formation of serotonin more efficiently than dopamine (PubMed:20098687). Displays no activity to tyrosine (PubMed:20098687). Variation in the synthesis of bioamines may be a factor contributing to natural variation in life span (PubMed:12881721)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR010977 Aromatic_deC
IPR002129 PyrdxlP-dep_de-COase
IPR015424 PyrdxlP-dep_Trfase
IPR015421 PyrdxlP-dep_Trfase_major
IPR015422 PyrdxlP-dep_Trfase_small
IPR021115 Pyridoxal-P_BS