Protein Name:
Guanine nucleotide-binding protein G(i) subunit alpha-2
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UniprotKB/SwissProt ID: P04899 (P04899)
Gene Name:
GNAI2
Organism: Homo sapiens (Human)
Function: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. May play a role in cell division Regulates the cell surface density of dopamine receptors DRD2 by sequestrating them as an intracellular pool
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell membrane. Membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P04899
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
112 |
DDARQLFALS C TAEEQGVLPD |
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| 2 |
140 |
RLWADHGVQA C FGRSREYQLN |
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| 3 |
326 |
DTKEIYTHFT C ATDTKNVQFV |
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| 4 |
66 |
IHEDGYSEEE C RQYRAVVYSN |
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