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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Catalase

UniprotKB/SwissProt ID: P04762 (P04762)

Gene Name: Cat

Organism: Rattus norvegicus (Rat)

Function: Catalyzes the degradation of hydrogen peroxide (H(2)O(2)) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Peroxisome matrix

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR018028 Catalase
IPR040333 Catalase_3
IPR024708 Catalase_AS
IPR024711 Catalase_clade1/3
IPR011614 Catalase_core
IPR002226 Catalase_haem_BS
IPR010582 Catalase_immune_responsive
IPR020835 Catalase_sf

The S-nitrosylation sites of P04762

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 232 LVNANGEAVY C KFHYKTDQGI   
2 377 GPNYLQIPVN C PYRARVANYQ   
3 460 VLNEEERKRL C ENIANHLKDA